Chromosome Polymorphism , A Significant Factor in Recurrent Pregnancy Loss : Redcliffe Labs Study

Approximately 33.7 per cent of couples experiencing recurrent pregnancy loss and primary infertility exhibited a higher prevalence of chromosome polymorphisms

Redcliffe Labs, an omnichannel diagnostics service provider in India on Sunday unveiled findings from a groundbreaking study indicating chromosome polymorphism (CPM) as a noteworthy contributor to recurrent pregnancy loss. Led by Dr Ashish Fauzdar and his team, the study analysed 1,400 individuals, including 700 couples diagnosed with recurrent pregnancy loss, the diagnostics service provider said in a press statement.

The research sheds light on a previously overlooked aspect of pregnancy loss, with traditional views regarding chromosome polymorphisms (CPM) being challenged. While these polymorphisms were once considered benign variants, the study's results suggest otherwise. Remarkably, approximately 33.7 per cent of couples experiencing recurrent pregnancy loss and primary infertility exhibited a higher prevalence of chromosome polymorphisms.

Dr Ashish Fauzdar, Head of Clinical Genomics and Cytogenetics at Redcliffe Labs, emphasised the significance of these findings, stating, "Our study marks a pivotal milestone in understanding the underlying causes of recurrent pregnancy loss."

"The elevated prevalence of chromosomal polymorphism highlights its substantial role in pregnancy complications, urging for further research and tailored clinical interventions."

Despite the study's groundbreaking implications, the researchers advocate for a cautious interpretation of the results. While chromosomal polymorphism may offer insights into recurrent pregnancy loss, additional robust evidence is necessary for conclusive understanding. Nonetheless, the study's findings are poised to inform clinical practices, enabling healthcare professionals to provide targeted counselling and interventions for couples navigating unexplained recurrent pregnancy loss.

 

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